The Effects of D-lysergic Acid Diethylamide Tartrate (lsd-25) on the Cholinesterases and Monoamine Oxidase in the Spinal Cord: a Possible Factor in the Mechanism of Hallucination.

'Candyflipping': synergistic discriminative effect of LSD and MDMA.

The co-administration of D-lysergic acid diethylamide (LSD; 'Acid') and 3,4-methylenedioxymethamphetamine (MDMA; 'Ecstasy'; 'XTC'), has reached a prevalence that has allowed for the street terminology 'candyflipping' to describe the combination. Internet sites indicate a significant enhancement of central effects with their simultaneous use. In this preliminary observation, male Fawn-Hooded rat...

D-lysergic acid diethylamide (LSD-25): a survey of the literature.

LSD: effect on monoamine metabolites in rat prefrontal cortex.

Lysergic acid diethylamide (LSD) has been studied extensively with respect to its actions upon monoamine pathways. The central 5-hydroxytryptamine (5HT) system has been the object of the most extensive investigation (1-3), but catecholamine systems have also received substantial attention (4,5). Nearly two decades of research point to the conclusion that LSD impedes transmission in 5HT-containi...

Effect of a chiral 4-alkyl substituent in hallucinogenic amphetamines.

The potency of hallucinogenic amphetamine derivatives of the 1-(2,5-dimethoxy-4-alkylphenyl)-2-aminopropane type drops dramatically when the length of the 4-alkyl substituent exceeds propyl or when the substituent is branched. This investigation was directed toward evaluating changes in behavioral and biochemical pharmacology resulting from introducing chirality into the 4-alkyl group of such a...

Effect of lysergic acid diethylamide (LSD-25) on morphine induced bradycardia.

Several antagonistic interactions between morphine and LSD-25 (lysergic acid diethylamide) have been demonstrated. LSD-25 antagonizes morphine induced analgesia in rats (1) and emesis in dogs (2). It also blocks the miotic action of morphine (3). On the other hand morphine blocks LSD-25 induced pyre xia in rabbits (4) and the central hypotensive effect of LSD-25 in dogs (5). Morphine produces m...